Endocrine Abstracts

Ectopic secretion of corticotropin(ACTH) by nonpituitary tumors accounts for 10–15% of ACTH dependent Cushing’s syndrome (CS). Generally it is difficult to localize the ACTH secreting tumor by conventional imaging methods because these tumors are often small in size. Here we present a case of ectopic ACTH syndrome diagnosed with octreotide scan.Case: A 26-year-old male patient presented with moon face, purplish striae, supraclavicular fat pads ...

Mixed medullary-follicular carcinomas (MMFC) of the thyroid are rare tumors which represents <0.15% of all thyroid tumors showing the morphological and immunochemical properties of both parafollicular and follicular cell lineages. Cases were immunoreactive for both calcitonin and thyroglobulin.Case 1: A 25-year-old female patient referred us for evaluation of a thyroid mass located on the left lobe. Ultrasonography (US) revealed 38 mm solid isoechoic...

Immune supressive patients due to any cause (disease, medication, etc.) rarely have autoimmune diseases. In this presentation, two patients diagnosed with Graves’ disease and subacute thyroiditis while taking cyclosporine therapy will be discussed.Case 1: A 47-year-old female patient applied with weight loss, sweating and tremor. She had been on cyclosporine therapy for 3 years because of hypoplastic anemia. In laboratory tests; TSH: 0.005 uIU/ml (0...

Background: Primary empty sella is an anatomical term defining the herniation of subarachnoid space within the sella turcica without an underlying factor such as pituitary tumor, surgery, irradiation or trauma.Patients and methods: We retrospectively evaluated clinical, hormonal and radiological data of the patients with primary empty sella syndrome followed in our institution between 2001 and 2012.Results: Ninety-four patients (80...

Introduction: The growth promoting effects of GH and IGF1 has lead to increasing number of cancer surveillence studies in acromegaly so far. We herein aimed to present the prevalance of cancer in acromegaly patients followed in our institution.Patients and design: We retrospectively analyzed medical records of 151 patients with acromegaly (83 females) followed in our department from 2001 to 2012.Results: Overall, cancer was detecte...

Objective: To compare the roles of inferior thyroid artery (ITA) peak systolic and end-diastolic velocities (PSV and EDV) measured by color flow Doppler ultrasonography (CFDUSG), TSH receptor antibody (TRAb) measured by M22 based ELISA and Tc-99m pertechnetate uptake for differential diagnosis between Graves’ disease (GD) and silent thyroiditis (ST).Methods: One hundred and fifty previously untreated subjects with GD (111 female, 39 male, mean age 3...

Introduction: Elephantiasis nostras verrucosa (ENV) is a rare, chronic, deforming disorder characterized by hyperkeratosis and papillomatosis of the epidermis with underlying woody fibrosis of the dermis and subcutaneous tissue resulting from chronic nonfilarial lymphoedema. Lymphatic obstruction can be primary or due to various causes such as surgery, tumour, radiation, congestive heart failure or obesity. However, to the best of our knowledge, it has not been reported as a p...

Introduction: Measles virus infections generally occur in childhood, but infections in adolescence and adulthood can lead to complications.Case report: A previously well 28-year-old woman had suffered from nausea, vomiting and generalized fatique for one day before being transferred to our emergency department in a confused state. A diagnosis of type 1 diabetes mellitus (T1D) complicated by ketoacidosis was made based on markedly decreased serum C-peptid...

Although obesity is a powerful risk factor for developing metabolic syndrome (MetS), it is not present in all obese individuals. Increased visceral adipose tissue is the hallmark of this syndrome. In this cross sectional survey abdominal bioelectrical impedence was used to measure the visceral adipose tissue (VAT) and trunk fat percentages (TF%) in participants. A total of 286 patients (196 female and 90 males) were enrolled in the study. In both sexes VAT was significantly po...

Aim: We aimed to compare the cut off values, defined to express the excess total body fat (TBF) percentange and increased fat mass index (FMI) as predictors of metabolic syndrome (MS).Subjects and methods: A total of 162 obese (body mass index (BMI) >30 kg/m2) subjects’ TBF were measured by ‘Tanita TBF 300 Body Composition Analyzer’. Patients were divided into two groups called normal obese (NO) and fatty obese (FO) accordin...